Innate antiviral immunity is impaired in young patients with hand foot and mouth diseases
نویسندگان
چکیده
منابع مشابه
Innate antiviral immunity is impaired in young patients with hand foot and mouth diseases
Results The expression levels of TLR3 mRNA in HFMD patients were significantly reduced (6.05±1.26) compared with the non-infection children (7.05±0.96), P<0.001, and the furthermore decreased was found in the patients with complications (5.79±1.15). While, the expressions of MDA5 mRNA in all patients including without complications (4.64±0.49) and with complications (4.60 ±0.48) were markedly h...
متن کاملHand Foot and Mouth Disease
Hand foot and mouth disease is an acute viral illness caused by the Coxsackie virus. The contagious nature of the disease is threatening as the disease primarily affects the children of school going age. As the name suggests, typical lesions will be seen over the hands, feet and in the oral cavity. The child gets irritated, febrile and lethargic. Oral lesions can add up to the general weakness ...
متن کاملHand Foot and Mouth Disease
Hand foot and mouth disease is an acute viral illness caused by the Coxsackie virus. The contagious nature of the disease is threatening as the disease primarily affects the children of school going age. As the name suggests, typical lesions will be seen over the hands, feet and in the oral cavity. The child gets irritated, febrile and lethargic. Oral lesions can add up to the general weakness ...
متن کاملHand foot and mouth disease.
with fever, malaise and asymptomatic oro-cutaneous lesions for the past 3-4 days, after being involved in cleaning activity of a fish pond. On examination he was febrile (temperature 100oF) with no lymphadenopathy. Oral cavity showed aphthae-like lesions having small yellowish-white shallow necrotic vesicles surrounded by red areola over palate, buccal and labial mucosae (Fig.1). Cutaneous lesi...
متن کاملMitochondria and antiviral innate immunity.
Mitochondria, dynamic organelles that undergo continuous cycles of fusion and fission, are the powerhouses of eukaryotic cells. Recent research indicates that mitochondria also act as platforms for antiviral immunity in vertebrates. Mitochondrial-mediated antiviral immunity depends on activation of the retinoic acid-inducible gene I (RIG-I)-like receptors signal transduction pathway and the par...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2011
ISSN: 1753-6561
DOI: 10.1186/1753-6561-5-s6-p45